Thursday, March 11, 2010

Genetic clue may help explain FTD risk

A gene on chromosome 7 may increase a person's risk of developing frontotemporal lobe dementia, according to an international team of scientists writing in the journal, Nature Genetics. Their work compared the brains of 515 individuals with FTD with the brains of 2,509 healthy people.

"We found a specific genetic change that was associated with an increased risk of the disease," co-author Maria Grazia Spillantini, of the University of Cambridge, told the Telegraph. “A better understanding of how the gene is involved could identify a new approach to tackle this disease.”

The paper lists FTD as the second most common cause of presenile dementia, which is dementia occuring in people younger than age 65.


The BBC story.

The Telegraph story.

Read the journal abstract (to read the article incurs a fee.)

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